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The twitching is all over my body in the upper area now as well and my muscles are fatigued and sore all of the time and I just don't know how I still have strength. ALS News Today Forums. A gradual onset of progressive muscle weakness - which is generally painless - is the most common initial symptom in ALS. I was convinced i had ALS or MS it took me over 1 year with several Doctors and Neurological visits with MRI and EMG which all came back clear. However, repeated episodes of fasciculations could be a sign of a neuromuscular disorder such as amyotrophic lateral sclerosis (ALS). Hi All. Signs and Symptoms. The disease belongs to a group of disorders known as motor . You know from being here that one ALS relative does not put you at increased risk. This is termed as 'bulbar onset' ALS. The twitches. Just watch any basketball game: it seems there's always somebody on the floor dealing with a significant leg cramp. Muscle Twitches: MS and Other Possible Causes - Verywell Health Symptoms at this stage are generally limited to a particular part of the body, and often first begin in the arms or hands, making daily . There are people who have been diagnosed who say they started out with twitching as their first symptoms. My muscle twitching started in my 20s because of very severe stress and anxiety. ALS News Today Moderator Participant Many people suffer from fasciculations or muscle twitching, and most of the time, it's caused by drinking too much coffee, a lack of sleep or a trapped nerve. Pain in legs getting worse regular twitching, mainly in legs, but also in other parts of body. Scared about ALS! - Neurology - MedHelp Struggling. twiching right pinky finger - Neurology - MedHelp Living with ALS - ALS Forums Weight loss is usually present due to loss of muscle. The hallmark of ALS is muscle failure which, thankfully, you don't have. Suspected ALS. Struggling - Motor Neurone Disease Association Forum 22 October 2020, 17:44. EIN # 04-3462719 There are people in their 20s saying they have been diagnosed with the illness. Reasons Your Forearm Muscles Are Twitching: ALS Possible?